ABSTRACT
The worldwide outbreak of SARS-CoV-2 infection has necessitated mandatory use of face masks, personal protective equipment and intake of a healthy diet for immunity boosting. As per WHO's recommendation, continuous use of masks has been proven effective in decreasing the SARS-CoV-2 infection rate. The present study reports on the bacterial filtration efficacy (BFE) of a novel 4-ply functionalized non-woven face mask. We synthesized a polypropylene-based fabric with inner layers of melt-blown fine fibres coated with polylactic acid and immune-boosting herbal phytochemicals. Experimental studies on the synthesized face mask demonstrated a BFE of greater than 99% against Staphylococcus aureus (a bacterium species frequently found in mammalian respiratory tract). A thorough computational analysis using LibDock algorithm demonstrated an effective docking performance of herbal phytochemicals against harmful virus structures. More importantly, the face mask also showed sufficient and stable breathability as per regulatory standards. A breathing resistance of 30 Pa at an aerosol flow rate of 30 l h-1 was reported under standard temperature and pressure conditions, indicating a high potential for real-world applications.
ABSTRACT
The emergence of COVID-19 pandemic has severely affected human health and world economies. According to WHO guidelines, continuous use of face mask is mandatory for personal protection for restricting the spread of bacteria and virus. Here, we report a 3-ply cotton-PLA-cotton layered biodegradable face-mask containing encapsulated phytochemicals in the inner-filtration layer. The nano-fibrous PLA filtration layer was fabricated using needleless electrospinning of PLA & phytochemical-based herbal-extracts. This 3-layred face mask exhibits enhanced air permeability with a differential pressure of 35.78â¯Pa/cm2 and superior bacterial filtration efficiency of 97.9% compared to conventional face masks. Close-packed mesh structure of the nano-fibrous mat results in effective adsorption of particulate matter, aerosol particles, and bacterial targets deep inside the filtration layer. The outer hydrophobic layer of mask exhibited effective blood splash resistance up to a distance of 30â¯cm, ensuring its utilization for medical practices. Computational analysis of constituent phytochemicals using the LibDock algorithm predicted inhibitory activity of chemicals against the protein structured bacterial sites. The computational analysis projected superior performance of phytochemicals considering the presence of stearic acid, oleic acid, linoleic acid, and Arachidic acid exhibiting structural complementarity to inhibit targeted bacterial interface. Natural cotton fibers and PLA bio-polymer demonstrated promising biodegradable characteristics in the presence of in-house cow-dung based biodegradation slurry. Addition of jaggery to the slurry elevated the biodegradation performance, resulting in increment of change of weight from 07% to 12%. The improved performance was attributed to the increased sucrose content in biodegradation slurry, elevating the bacterial growth in the slurry. An innovative face mask has shown promising results for utilization in day-to-day life and medical frontline workers, considering the post-pandemic environmental impacts.
ABSTRACT
Surging dismissal of plastics into water resources results in the splintered debris generating microscopic particles called microplastics. The reduced size of microplastic makes it easier for intake by aquatic organisms resulting in amassing of noxious wastes, thereby disturbing their physiological functions. Microplastics are abundantly available and exhibit high propensity for interrelating with the ecosystem thereby disrupting the biogenic flora and fauna. About 71% of the earth surface is occupied by oceans, which holds 97% of the earth's water. The remaining 3% is present as water in ponds, streams, glaciers, ice caps, and as water vapor in the atmosphere. Microplastics can accumulate harmful pollutants from the surroundings thereby acting as transport vectors; and simultaneously can leach out chemicals (additives). Plastics in marine undergo splintering and shriveling to form micro/nanoparticles owing to the mechanical and photochemical processes accelerated by waves and sunlight, respectively. Microplastics differ in color and density, considering the type of polymers, and are generally classified according to their origins, i.e., primary and secondary. About 54.5% of microplastics floating in the ocean are polyethylene, and 16.5% are polypropylene, and the rest includes polyvinyl chloride, polystyrene, polyester, and polyamides. Polyethylene and polypropylene due to its lower density in comparison with marine water floats and affect the oceanic surfaces while materials having higher density sink affecting seafloor. The effects of plastic debris in the water and aquatic systems from various literature and on how COVID-19 has become a reason for microplastic pollution are reviewed in this paper.